Which drugs are nephrotoxic?

Table of Contents

The nephrotoxic effects of cyclosporine, aminoglycoside antibiotics, cisplatin, amphotericin B, beta-lactam antibiotics and indomethacin are reviewed. These drugs were chosen because they are among the most frequent causes of renal injury in children. In addition, their nephrotoxicity is caused by different mechanisms.

Which drug is associated with renal toxicity?

Table 1

Medication	Drug category	Renal toxicity
Acyclovir	Antiviral	Acute interstitial nephritis, crystal nephropathy
Allopurinol	Hypouricemic agent	Acute interstitial nephritis
Aspirin	Non-narcotic analgesic	Chronic interstitial nephritis
Amitriptyline	Antidepressant	Rhabdomyolysis

Is omeprazole nephrotoxic?

INTRODUCTION AND AIMS: Omeprazole is a proton pump inhibitor (PPI) for patients with gastroesophageal reflux and peptic ulcer. It was not considered nephrotoxic, but recent case reports and epidemiological studies suggest a paradigm change.

Is linezolid nephrotoxic?

Because of side effects of linezolid, i.e. nephrotoxicity, we recommend close monitoring of kidney function tests when linezolid therapy is attempted. Clinicians should be aware of these potential life- threatening adverse reactions and monitor kidney function while patients are using linezolid.

Which antibiotic is least nephrotoxic?

Among these treatment groups, tobramycin was the least nephrotoxic of the aminoglycosides.

Is esomeprazole Nexium?

Nexium (esomeprazole) is a prescription drug used to treat GERD, ulcers and other stomach acid-related conditions. It belongs to a class of drugs called proton pump inhibitors. Common Nexium side effects include headache and nausea.

Is captopril nephrotoxic?

Alfuzosin may increase the hypotensive activities of Captopril. The risk or severity of hypotension, hyperkalemia, and nephrotoxicity can be increased when Aliskiren is combined with Captopril. The risk of a hypersensitivity reaction to Allopurinol is increased when it is combined with Captopril.