What is DNA based medicine?
Taking a much more precise approach to treatment means that for some diseases, doctors can prescribe drugs based on a person’s DNA. This so-called precision medicine is breaking new ground in the treatment of some diseases. And it could change medicine for good.
What medications change your DNA?
Common Drugs Impacted by Genetics
- Fluorouracil (Adrucil®) Fluorouracil (5-FU) is one of the most successful and widely used chemotherapy drugs.
- Clopidogrel (Plavix®)
- Tamoxifen (Nolvadex®)
- Atomoxetine (Strattera®)
- Warfarin (Coumadin®)
How can DNA be used in personalized medicine?
The story of personalized medicine begins with the unique set of genes you inherited from your parents. Genes are stretches of DNA that serve as a sort of instruction manual telling your body how to make the proteins and perform the other tasks that your body needs.
Does DNA help medicine?
Because we can know a patient’s DNA sequence (and the protein it codes for) we can develop drugs specifically for that person. This is particularly important in cancer because the DNA gets mutated the same way in specific cancers every time.
What is meant by Personalised medicine?
Personalised medicine: a move away from a ‘one size fits all’ approach to the treatment and care of patients with a particular condition, to one which uses new approaches to better manage patients’ health and target therapies to achieve the best outcomes in the management of a patient’s disease or predisposition to …
Why is the discovery of DNA important in medicine?
Knowing the structure of DNA was important to medicine, because scientists could now identify the parts that caused hereditary diseases. In 1990, scientists led by James Watson launched the Human Genome Project to identify the complete set (over 3 billion pairs) of DNA which makes up human beings.
How has the discovery of DNA helped modern medicine?
DNA can be used to screen people for genetic diseases, eg breast cancer. It has also been used to reverse mutations that cause blindness, to stop cancer cells from multiplying and make some cells resistant to AIDS .
What is IND and NDA?
The Investigational New Drug (IND) application falls into the first category, while the New Drug Application (NDA), Abbreviated New Drug Application (ANDA), and Biologics License Application (BLA) fall into the second category.
What is CDM PV?
Clinical Data Management (CDM) Pharmacovigilance (PV)