What is the strongest JWH?
The highest concentrations of JWH-018 N-5-OH M was 85 pg/mg; in this case, the JWH-018 concentration was 151 pg/mg. Overall, in samples positive both to JWH-018 and JWH-018 N-5-OH M, parent drug-to-metabolite ratios were highly variable, ranging from 1.1 to 62.8.
Where is JWH-018 found?
JWH-018 is a potent non-selective cannabinoid receptor agonist that was found in the first generation of spice products (1, 2). The present experiments yielded three primary findings.
Is JWH-018 legal in the US?
Both substances are dangerous to an individual’s health, which is why both JWH-018 and marijuana are both listed as Schedule I Controlled Substances, which are banned from use.
What Colour is JWH-018?
|IU Chem Holding Co.||bright yellow|
Who made JWH-018?
John W. Huffman
History. John W. Huffman, an organic chemist at Clemson University, synthesized a variety of chemical compounds that affect the endocannabinoid system. JWH-018 is one of these compounds, with studies showing an affinity for the cannabinoid (CB1) receptor five times greater than that of THC.
What does JWH stand for?
|JWH||John Wesley Harding|
|JWH||Journal of Women’s History|
|JWH||Julia Ward Howe (author)|
|JWH||John Wieland Homes (Smyrna, GA)|
Is JWH-018 water soluble?
|Molar mass||341.454 g·mol−1|
|3D model (JSmol)||Interactive image|
|Solubility in water||hydrophobic, n/a mg/mL (20 °C)|
What is JWH made of?
JWH-018 is the 18th compound that Huffman’s research group synthesized in a series of more than 470 analogs and metabolites of ∆9-tetrahydrocannabinol (THC), the active component of marijuana. Huffman created these compounds to study their interactions with the cannabinoid receptors in the brain.
Is JWH 073 legal?
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors….JWH-073.
How do you dissolve JWH-018?
JWH 018 N-(1-ethylpropyl) isomer is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas.
What does JWH-018 feel like?
JWH-018 may cause intense anxiety, agitation, and, in rare cases (generally with non-regular JWH users), has been assumed to have been the cause of seizures and convulsions by inhibiting GABA neurotransmission more effectively than THC.
Is indole a controlled substance?
1-(5-Fluoropentyl)-3-(2-iodobenzoyl)indole AM-694 is a DEA Schedule I controlled substance. Substances in the DEA Schedule I have no currently accepted medical use in the United States, a lack of accepted safety for use under medical supervision, and a high potential for abuse.