What is the prognosis of tuberculosis?
Without treatment, TB is a severe and potentially fatal disease. After 5 years without treatment, the outcome of smear-positive pulmonary TB (PTB) in non-HIV-infected patients is as follows1: 50 to 60% die (case fatality ratio (CFR) for untreated TB); 20 to 25% are cured (spontaneous cure);
Can extrapulmonary TB be cured?
In contrast with PTB treatment, cure for EPTB is difficult to define. Moreover, there are no established criteria for the end of treatment. In case of studies on TB lymphadenitis, residual lymph nodes at the end of treatment have usually been used for assessing treatment outcomes.
How serious is Mycobacterium tuberculosis?
Tuberculosis (TB) is a potentially serious infectious disease that mainly affects the lungs. The bacteria that cause tuberculosis are spread from person to person through tiny droplets released into the air via coughs and sneezes.
Does extrapulmonary TB spread?
Children with TB or people with a TB infection that occurs outside the lungs (extrapulmonary TB) do not spread the infection.
What is the last stage of tuberculosis?
Stage Three The body brings in more immune cells to stabilize the site, and the infection is under control. At least nine of ten patients infected with Mycobacterium tuberculosis stop at stage 3 and do not develop symptoms or physical signs of active disease.
How long do you treat extrapulmonary TB?
The recommended treatment for drug-susceptible EPTB is with isoniazid, rifampin, ethambutol and pyrazinamide for 6 months, with the exception of tuberculous meningitis which is treated with 9 to 12 months of therapy .
How long do we treat extrapulmonary TB?
Purpose: The recommended duration of pulmonary tuberculosis therapy is 6 months.
Can latent TB be cured?
The bacteria remain alive but not growing. This is called inactive or Latent TB Infection (LTBI). TB can be cured with antibiotic medications.
Where does Mycobacterium tuberculosis come from?
The origin of M. tuberculosis, the causative agent of TB, has been the subject of much recent investigation, and it is thought that the bacteria in the genus Mycobacterium, like other actimomycetes, were initially found in soil and that some species evolved to live in mammals.
How do you get extrapulmonary tuberculosis?
Extrapulmonary tuberculosis (EPTB) is an infectious disease caused by Mycobacterium tuberculosis that occurs in organ systems other than the lungs. Epidemiologic risk factors include birth in high TB-prevalent countries, exposure at place of residence/work in an institutional setting, and homelessness.
How is extrapulmonary TB treated?