What is Dacogen used to treat?

What is Dacogen used to treat?

This medication is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS may have problems such as infections, anemia, and easy bleeding/bruising. Decitabine is a chemotherapy drug.

What are the side effects of Dacogen?

Common side effects of Dacogen include:

  • headache,
  • dizziness,
  • tired feeling,
  • fatigue,
  • fever,
  • nausea,
  • vomiting,
  • stomach pain,

What type of drug is Dacogen?

Dacogen is the trade name for decitabine. In some cases, health care professionals may use the trade name Dacogen when referring to the generic drug name decitabine. Drug type: Decitibine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.

What is the cost of dacogen?

The cost for Dacogen intravenous powder for injection 50 mg is around $1,885 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

How effective is Dacogen?

Overall anticancer responses were achieved in 17% of patients treated with decitabine, compared with 0% in patients treated with supportive care. Hematologic (blood) improvement occurred in 12% of patients treated with Dacogen, compared with 7% of patients treated with supportive care.

Does Dacogen cause hair loss?

However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Hair loss. Constipation, diarrhea, stomach pain, upset stomach, throwing up, or feeling less hungry.

What is the life expectancy of a person with MDS?

Survival statistics for MDS

IPSS-R risk group Median survival
Very low 8.8 years
Low 5.3 years
Intermediate 3 years
High 1.6 years

Is decitabine a chemotherapy?

DECITABINE (dee SYE ta been) is a chemotherapy drug. This medicine reduces the growth of cancer cells.

Who manufactures decitabine?

About Dacogen® (decitabine) Dacogen® was developed by SuperGen, Inc., (now Astex Pharmaceuticals, Inc.) as a therapeutic agent for myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) possessing cell differentiation-inducing activity through the inhibition of DNA methylation.

What is the difference between azacitidine and decitabine?

The results showed that, in MDS, AZA showed better AML-free survival, whereas DAC demonstrated higher CR and ORR, and AZA obtained better OS with lower toxicity. In AML, DAC had the possibility of achieving superior CR, ORR, and OS, while the toxicity was relatively higher.

How long does it take decitabine to work?

How long does it take for patients to respond to treatment? In the clinical study, the median time for patients to achieve some level of remission for either CR or CRh was 2 months (with a range of 0.8 to 4.2 months).

Can you live 20 years with MDS?

With current treatments, patients with lower-risk types of some MDS can live for 5 years or even longer. Patients with higher-risk MDS that becomes acute myeloid leukemia (AML) are likely to have a shorter life span.